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Exuberant molluscum contagiosum in HIV disease

Dr Rohit Kothari1, MD, Dr Sanjay Khare, MD2

1Assistant Professor, Dermatology, Command Hospital Air Force, Bengaluru, India
2Professor, Dermatology, Mahatma Gandhi Memorial Medical College, Indore, India

Received Date: 19/11/2022; Published Date: 12/12/2022.

*Corresponding author: *Dr Rohit Kothari, Assistant Professor, Dermatology, Command Hospital Air Force, Bengaluru, India

A 36-year-old female presented with multiple skin-colored nodules around the eyes associated with difficulty in vision from right eye for five months (Panel A and B). She also gave history of significant weight loss. There was no history of high-risk sexual behavior, intravenous drug abuse, or blood transfusion. Bedside Tzanck smear showed multiple Henderson Peterson bodies. Lab investigations revealed HIV positive status with a CD4 count of 98 cells/µl. She was diagnosed as giant molluscum contagiosum (MC) in a HIV positive patient. MC in HIV patients tend to present with multiple lesions (≥50-100) or giant forms (≥5 cm) which commonly involves the face and may be refractory to conventional therapies. It may also develop as a part of immune reconstitution inflammatory syndrome and is usually associated with low CD4 count. She was counselled and started on HAART (Tenofovir, Lamivudine and Efavirenz). Follow-up at 3-month revealed complete regression of the lesions.

Figure A

Figure B

Conflict of interest: None for all authors

Acknowledgement: The patient in this manuscript has given written informed consent to the publication of her case details and photographs.

Data availability statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.

Author contribution statement: The manuscript has been read and approved by all the authors and each author believes that the manuscript represents honest work.