Indexing
Volume 3
Issue 2
Elevated factor VIII Case report: A complicating factor for acute Coronary Syndrome
Atherothrombosis is the main cause of coronary syndrome, due to
the presence of classic cardiovascular risk factors. In some patients,
other factors can be responsible for arterial or venous thrombosis. The
presence of other thrombophilic risk factors such as high homocysteine, Factor VIII (FVIII), lupus anticoagulant and genetic polymorphisms of hemostatic factors (Factor II and Factor V Leiden) should
be suspected as responsible or adjuvant mechanism (1,2,3). FVIII is
an essential cofactor in the coagulation cascade; FVIII overexpression
can trigger thrombotic disorders and complicate acute coronary syndrome (ACS).
DOI: 10.55920/IJCIMR.2022.03.001120
Is my profession a risk for my lungs? - Unusual case of Hypersensitivity Pneumonitis.
A 68-year-old male was referred to the pulmonary clinic with progressive shortness of breath (SOB) for the last six months. The SOB has
worsened in the two months prior to his presentation. His SOB was
exertional, especially when he climbed stairs. He had undergone an
extensive workup for cardiac causes, but the results were negative for
such causes. The patient never smoked and reported no industrial
exposure, pets, or pigeons at home. No other exposure history to any
organic or inorganic agents was reported based on a detailed structured questionnaire.
DOI: 10.55920/IJCIMR.2022.03.001119
Hemifacial Microsomia: Case series and overview
A 15 years old female was referred to department of Radio-diagnosis
for cross-sectional Non-contrast CT scan of Face with 3D reconstruction by department of plastic surgery. Patient has complaints of facial
asymmetry with skin tags in right pre-auricular region since birth
(Figure 1 and 2). NCCT with 3D reconstruction reveals small sized
right mandibular ramus, and both right condylar and coronoid process
however condylar process articulating with glenoid fossa with reduced
right temporomandibular joint as compared to left side (Figure).
DOI: 10.55920/IJCIMR.2022.03.001118
Nutrition during pregnancy in the Eritrean context
A woman’s nutritional status prior to and during pregnancy influences
the baby’s and her own health. A woman's nutritional status should be assessed preconceptionally with the goal of optimizing maternal,
fetal, and infant health. Pregnancy-related dietary changes should begin prior to conception, with appropriate modifications across preg-
nancy and during lactation. During pregnancy, women should eat
an extra meal per day (in their second and third trimester, no extra
needed in the first one) as well as reduce physical workload during
the final months of pregnancy in order to gain enough weight. The
recommended intake is adding 0, 340, and 452 kcal/day to the estimated nonpregnant energy requirements in the first, second, and third
trimesters, respectively
DOI: 10.55920/IJCIMR.2022.03.001117
OUTPATIENT STENTING OF POST SLEEVE GASTRECTOMY LEAKS
Between January and June 2022, 2 patients, a 34- year-old-man and
a 22 year-old- woman, presented, one month and 4 months respec-
tively, following laparoscopic sleeve gastrectomy, a type II (1) gastric
leak documented on CT scan. The 2 patients were directly addressed for endoscopic internal drainage of the leak. The orifice of the leak was
identified under the gastroesophageal junction and catheterized, under endoscopic guidance by a guidewire, followed by the introduction
of a 7Fr,7 cm plastic pancreatic endoprosthesis (Geenen pancreatic
stent, Cook, Limerick) in the anomalous tract. (Figure 1) Patients were
discharged directly after the procedure. Oral antibiotic was prescribed as well as early soft oral alimentation.
DOI: 10.55920/IJCIMR.2022.03.001116
Female Runner with An Elevated Troponin
45-year-old female runner with a past medical history of hypertension
presented to the Emergency Department with sudden onset subster-
nal chest pain and diaphoresis after one of her usual running sessions.
EKG showed normal sinus rhythm with nonspecific T-wave changes. Initial troponin I was 1.16 ng/mL, she was admitted to the Coronary
Care Unit and started on a heparin drip. Her troponin I peaked at 38 ng/mL. Coronary angiography was performed the following day
which suggested Type II spontaneous coronary artery dissection
(SCAD) involving the obtuse marginal artery.
DOI: 10.55920/IJCIMR.2022.03.001115
Asymptomatic Osteoid osteoma in the Mandible - A Case Report
Osteoid osteoma is defined as benign neoplasm1. It is the third most
common benign bone tumor and account for 10-14% of all benign
bone tumors after enchondroma and non-ossifying fibroma 2. They
occur most often in the lower extremities of the appendicular skeleton
(80%) 3. Their occurrence in the craniofacial skeleton is exceptionally
rare 3,4. The lesions are often symptomatic, and patients seek medical
help due to pain. Young adults under 30 years of age are usually affect-
ed 2,3.
DOI: 10.55920/IJCIMR.2022.03.001114
PREDICTING OF ENROLLMENT AS A PART OF RISK-BASED MANAGEMENT OF CLINICAL TRIALS
An obligatory stage before starting a clinical trial is to conduct a study
of the capabilities of clinical centers to implement the protocol - feasibility (Kibby M., 2011). The same author talks about the flexibility of
the concept of feasibility from sponsor to sponsor.
Poorly conducted feasibility study is a barrier to patient recruitment
(Parke J, 2022) and undergones the study to risk to be failure. Risks
which might be raised during the clinical trial is accepted by clini-
cal trials stakeholders and graduated accordingly (Risk classification
guide, 2022).
DOI: 10.55920/IJCIMR.2022.03.001113
Antibacterial activity of dew and Acacia gum on biofilm forming of Pseudomonas Aeruginosa
Waterborne and foodborne diseases have emerged as the major public health concerns across the globe. Food-borne diseases are major
health problems both in developed and developing countries (Abunna
et al.2016). Utilization of foods and water contaminated with certain
food and water pathogens such as fungi, bacteria, and viruses, is con-
sidered as a major source of foodborne illness human. Salmonella spp.,
Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa,
Staphylococcus aureus, Shigella spp., and Listeria monocytogenes,
are the most frequently reported foodborne pathogens from different
parts of the world (Hoiby et al.2010 and Hassett et al. 2010).
DOI: 10.55920/IJCIMR.2022.03.001112
Tuberculosis in Peritoneal Dialysis patients: A Diagnostic challenge.
Mycobacterium tuberculosis is a contagious infectious illness caused
by a tuberculosis complex mycobacterium, primarily Mycobacterium
tuberculosis or Koch's bacillus (KB) [1]. It is still a huge public health
issue across the world, particularly in underdeveloped nations [2]. It
is commonly seen in people with CKD. Peritoneal localization, which
is generally uncommon, has become a significant type in peritoneal
dialysis patients [3]. Positive diagnosis is challenging in this popula-
tion due to the non-specific clinical presentation [4].
DOI: 10.55920/IJCIMR.2022.03.001111
