Indexing
Volume 4
Issue 4
When a Duodenal GIST Reveals Multifocal Neurofibromatosis Type 1: A Case Report
Type 1 neurofibromatosis (NF1), also known as von Recklinghausen
disease, is the most common phakomatosis. It is an autosomal dominant genetic disorder caused by a mutation of the NF1 gene, located
on chromosome 17. The disease is mainly characterized by the presence of cutaneous, plexiform, or spinal neurofibromas, as well as a
predisposition to the development of various tumors, including gastrointestinal stromal tumors (GISTs).
DOI: 10.55920/IJCIMR.2024.04.001166
Reactive Histiocytic Dermatitis from Ponatinib
A 54-year-old male had BCR::ABL1 p190, TP53, IKZF1-mutated acute lymphoblastic leukemia with extramedullary disease of the clivus and
ribs. He received alkylating chemotherapy and ponatinib, followed by blinatumomab and ponatinib, achieving complete remission but with
minimal residual disease. He then attained complete molecular remission after undergoing myeloablative haploidentical-related stem cell
transplantation conditioned with cyclophosphamide and total body irradiation with posttransplant cyclophosphamide, mycophenolate
mofetil, and tacrolimus graft-versus-host disease prophylaxis. On day 60 post-transplant, he began a daily maintenance dose of 15 mg of
ponatinib.
DOI: 10.55920/IJCIMR.2024.04.001162
Gigantic Secondary Pelvic Chondrosarcomas: A Case Report
Hypertensive disorder of pregnancy (HDP) is a condition characterized by varying degrees of elevated blood pressure during pregnancy,
Chondrosarcoma is a malignant tumor of cartilage-forming cells.
We present a case of a 36-year-old female with an infiltrative, lytic
process involving the right hip, extending to the upper femoral diaphysis and pelvis, secondary to sarcomatous degeneration of an
exostosis.
DOI: 10.55920/IJCIMR.2024.04.001161
