Volume 4

Issue 3

Effect of Chimerism on Relapse in Stem Cell Transplantation

Chimerism guides the clinician about the patient's immune response after stem cell transplantation.Chimerism is studies in which unique DNA fragments in both the donor and recipient are used as markers using stem cell pre-transplant DNA samples.. Post-transplantation, the recipient is evaluated for these uniquely identifying DNA fragments. In the absence of donor DNA fragments detected in recipient samples, graft rejection can be considered.ultimately the recipient DNA frag ments are a proof of the recipient's hematopoiesis.
DOI: 10.55920/IJCIMR.2023.04.001158

The “Clot sign”, a valuable imaging clue for radiologists and surgeons

A 28-year-old female presented to the emergency department with acute abdominal pain in the right iliac fossa. Clinical examination revealed a pale and tachycardic patient with tenderness in the right iliac fossa. Following an ultrasound that showed a moderate amount of peritoneal fluid, an abdominal CT scan was requested, revealing hemoperitoneum with clot sign (Figure 1) and contrast extravasation in the pelvic region (Figure 2).
DOI: 10.55920/IJCIMR.2023.04.001157

Arthroscopic repair of full-thickness cartilage defects in horses with autologous nasal chondrocytes seeded in an injectable hydrogel: from preclinical development to clinical cases

Articular cartilage is frequently damaged as a result of trauma or degenerative joint disease, and because it is an avascular and poorly cellularized tissue in adults, its capacity for spontaneous repair is limited (Hanie et al., 1992; Hurtig et al., 1988; Vachon et al., 1986). Indeed, only osteochondral defects, which affect both the subchondral bone and cartilage exhibit a repair process that leads to the formation of fibrocartilage. This fibrocartilage does not however display the mechanical properties of native articular cartilage (Buckwalter and Mankin, 1998) and unfortunately degrades rapidly.
DOI: 10.55920/IJCIMR.2023.04.001156

Recurrent cutaneous myoepithelioma of the scalp case report: management and histological analysis.

Myoepithelial cell neoplasms consists of an uncommon group of tumors. These may be both malignant and benign. Even if rare there is a quite proper characterization. Actually, the best known is the salivary gland myoepithelioma, but recently extra salivary examples have been reported (1). In this clinical case, a cutaneous location of myoepithelioma (CM) is described. This is an even more under-recognized tumor that generally behaves in a benign fashion.
DOI: 10.55920/IJCIMR.2023.04.001154

Role of Ultrasonography in Peripheral Nerve Involvement in Leprosy: A Cross-sectional Study

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Two key components of the disease are skin and nerve involvement. Leprosy patients develop anaesthesia of hands and feet, which puts them at risk of developing deformity and contractures.(7) Loss of fingers and toes is caused by repeated injury in weak, anaesthetic limbs, and these visible deformities cause significant stigmatisation. Mononeuritis multiplexis a typical presentation of leprosy. (8) Diagnosis is based on the recognition of anesthetic skin lesions, identification of enlarged nerves, and the demonstration of the causative organism M leprae.
DOI: 10.55920/IJCIMR.2023.04.001153

Ultrasound Finding of Subclinical Joint and Tendon Inflammation of the Patients with Systemic Lupus Erythematosus

According to clinical manifestations, systemic lupus erythematosus (SLE) can be classified as a mild, moderate, or severe disease, which is significant for treatment selection. Musculoskeletal manifestations are considered mild, but in practice, they can often persist, relapse, and be resistant to treatment, requiring the use of multiple therapy modalities and potent immunosuppressants. Musculoskeletal manifestations occur in approximately 95% of patients, with around 50% experiencing them as the initial presenting symptom [1,2]. These manifestations can be symptomatic (clinically recognizable) or asymptomatic, causing significant disability and socio-economic consequences [3].
DOI: 10.55920/IJCIMR.2023.04.001152

Metastasis of hepatocellular carcinoma in the orbit as first manifestation of extrahepatic spread- A case report and review of the literature

Primary liver cancer is one of the most common malignancies globally, being the sixth cause of cancer and third in cancer-related mortality [1]. Its’ incidence is expected to rise even further by 2040 [1]. Hepatocellular carcinoma (HCC) consists of the 75-85% of all primary liver malignant neoplasms. Liver cirrhosis of any cause is the most important risk factor for HCC development [2]. Extrahepatic metastatic HCC was estimated at 15-50% [3-7] with the most common sites being the lungs (47-55%), lymph nodes (45-53%), bones (28-37%) and adrenal glands (11-12%) [8].
DOI: 10.55920/IJCIMR.2023.04.001151